[뉴스웍스=고종관 기자] Even if you are not obese, a study found that people with polycystic ovary syndrome are at least twice as likely to develop diabetes. The number of women with polycystic ovary syndrome in Korea is increasing every year, so caution is required.
Professor Park Hyun-tae and Ryu Gi-jin, a research team at Anam Hospital of Korea University University College of Medicine, found that, through a recent cohort study, women of normal weight regardless of obesity or body mass index (BMI) also have polycystic ovary syndrome, which increases the risk of type 2 diabetes. It was revealed on the 5th that it was confirmed.
The research team extracted data from 6811 women (ages 15-44) from the National Health Insurance sample cohort database for 10 years from 2003 to 2012. And after dividing these women into 1136 people with polycystic ovary syndrome and 5675 people in the control group, the possibility of developing diabetes was analyzed.
As a result, women with polycystic ovary syndrome had a 2.6-fold increase in risk of developing type 2 diabetes compared to the control group. On the other hand, there was no significant correlation between body mass index, family history, cholesterol level, and diabetes.
Polycystic ovary syndrome is a common endocrine disease that occurs in about 10% of women of childbearing age. Symptoms include chronic anovulation, menstrual abnormalities, and irregular bleeding, and are also the main causes of infertility. Hormonal abnormalities such as the hypothalamus or pituitary gland increase the secretion of male hormones in the ovaries, making ovulation difficult.
In general, polycystic ovary syndrome patients are more prone to obesity. Therefore, it is known that various metabolic diseases increase. However, a recent study reveals that Korean women do not follow this trend. Even with polycystic ovary syndrome, the percentage of normal weight is high, and the risk of developing type 2 diabetes increases just by having polycystic ovary syndrome regardless of obesity.
The characteristic of this study is that it utilized domestic big data. Therefore, it is expected to be able to present guidelines suitable for Koreans. For example, in a Finnish birth cohort study, type 2 diabetes increased only in obese cases of polycystic ovary syndrome, whereas in Australia, type 2 diabetes increased regardless of BMI. It has been proven that the correlation between polycystic ovary syndrome and diabetes onset differs according to characteristics such as country and race.
Professor Ryu said, “The previous study was mainly conducted on Western women with a high percentage of obese polycystic ovary syndrome.” I look forward to becoming,” he said.
The study was published in the latest issue of’Fertility and Sterility’, the journal of the American Society of Reproductive Medicine.