The world’s first development of technology to measure disease occurrence and elapsed time

Professor Kim Hyung-beom (right) of the Yonsei University School of Medicine is conducting an experiment on DNA sequence changes (Photo = Samsung Electronics).
Professor Kim Hyung-beom (right) of the Yonsei University School of Medicine is conducting an experiment on DNA sequence changes (Photo = Samsung Electronics).

Samsung Electronics announced on the 4th that the research team of Professor Hyungbeom Kim of Yonsei University College of Medicine developed the world’s first system to measure the time when life phenomena occurred by changing the DNA base sequence. Revealed.

Samsung Future Technology Promotion Project This research was conducted in collaboration with the research team of Professors Jeong In-kyung and Cho Seong-rae of the College of Medicine at Yonsei University, Professor Tae-Young Park of the Department of Applied Statistics at Yonsei University, and Professor Sung-ro Yoon of the Department of Electrical and Computer Engineering at Seoul National University.

The paper titled’Recording of elapsed time and temporal information about biological events using Cas9′, which contains the results of the study, describes biological phenomena such as diseases and aging. It was recognized as having made a breakthrough in accurately grasping when it occurs, and it was published in’Cell’, a world-renowned journal specializing in life sciences on the 3rd (US local time).

This is the first time that a research project supported by the Samsung Future Technology Promotion Project has been published in’Cell’. So far, there are 5 papers in’Nature’ and 6 articles of’Science’ that have been introduced in top international journals.

Using DNA sequence to identify when life phenomena such as diseases occur

According to the paper, when an organism becomes diseased, its DNA sequence changes. By finding out when the base sequence has changed, it is possible to track when the disease occurred, so that treatment according to the progression of the disease can be applied. For example, if you check the exact time when the human body was infected with a virus, you will be able to use appropriate treatment drugs according to the progression of the disease.

Prof. Hyungbeom Kim’s research team found that as time goes on, as the DNA sequence changes, the normal sequence decreases and the mutation increases.

Professor Kim Hyung-beom said, “By using the same principle as the radioisotope measurement method that measures the age of fossils, we can accurately grasp the time course of various phenomena occurring in living organisms.” “It can be used for “

Prof. Kim completed the patent registration for the technology in Korea in consideration of industrial use, and patents are pending overseas, including the United States. This research was selected as a project of the Samsung Future Promotion Project in June 2017 and is receiving support.

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The Samsung Future Technology Promotion Project aims to foster and support science and technology research that will be responsible for the future of Korea. This is a research support public service project that Samsung Electronics has been conducting with 1.5 trillion won contributions since 2013.

Details of the 2021’Designated Theme Project Competition’ will be disclosed on the Samsung Future Technology Promotion Program website (http://www.samsungstf.org/) on the 17th.





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