The Ministry of Food and Drug Safety (hereinafter referred to as the Ministry of Food and Drug Safety) explained the characteristics and principle of action of the Corona 19 vaccine so that the public could easily understand it.
Currently, rapid development of the Corona 19 vaccine is being promoted, and a variety of vaccine platform technologies are being used. The term’vaccine platform’ is a base technology for developing vaccines by only changing specific antigens or genetic information in the vaccine, which will greatly shorten the development period. I can.
Principles of preventing COVID-19 by vaccination (Data = Ministry of Food and Drug Safety)
When the COVID-19 vaccine is inoculated, the antigen components of the vaccine that have entered the human body stimulate immune cells (B cells). ▲ Make a neutralizing antibody that can remove the virus from the stimulated B cells and store it in the body. ▲When the Corona 19 virus invades through the respiratory tract, ▲The neutralizing antibody in the body will remove the invading Corona 19 virus.
Viral vector vaccine is a vaccine that induces an immune response by injecting an antigen gene into another virus template such as adenovirus, which is harmless to the human body, and producing an antigen protein in the body. Representatively, AstraZeneca vaccine and Janssen vaccine are expected to be introduced in Korea. .
Compared to RNA vaccines, it is relatively stable to heat, but since it uses live adenovirus, it requires a cold chain equivalent to live vaccine (4℃), and Janssen’s Ebola vaccine is the approved vaccine.
The RNA vaccine is a vaccine that induces an immune response by injecting an antigen gene in the form of RNA to generate an antigenic protein in the body. Representatively, there are Pfizer vaccine, Modena vaccine, etc., which will also be introduced.
In addition, according to the WHO, various types of Corona 19 vaccines are being developed at Cansino (viral vector vaccine) and Gamaleya Institute of Russia (viral vector vaccine).
The Ministry of Food and Drug Safety said, “In view of the high public interest in the Corona 19 vaccine, we will continue to provide information on the safety and effectiveness of the vaccine and make an effort to create an environment in which the Korean people can receive the vaccine with confidence.”
“In addition, we will do our best to use a safe vaccine through a thorough review and management of the safety and effectiveness of the vaccine applied for permission,” he said.