Hanmi Pharm announced on the 13th that the research result that the main component of the respiratory virus blocker’Hanmi Cold Mask Nasal Spray’, which is sprayed on the nose, effectively blocks the corona 19 (COVID-19) virus, etc., has been registered in international journals.
Scientific Report, an SCI-level international academic journal published by Nature, is based on the results of an in vitro cell experiment that evaluated the antiviral activity of lambdacarrageenan, conducted by the Korea Research Institute of Chemical Technology with the support of the Ministry of Science, Technology and Communication. (Scientific Reports).
Lambdacarrageenan, a naturally derived ingredient extracted from seaweed, is the main ingredient in the recently launched Hanmi Cold Mask Nasal Spray by Hanmi Pharmaceutical.
According to the paper, the researchers used’EC50′ (50) as an index to evaluate the antiviral activity of lambdacarrageenan against the virus that causes COVID-19 (SARS-CoV-2) and influenza viruses A and B, which are the main causes of pandemic flu. % Effective concentration) and’SI’ (Selectivity Index) were used.
First, in the SARS-CoV-2 virus test conducted on Vero cells (fibroblasts derived from monkey kidney epithelium), the EC50 value indicating antiviral activity was 0.9±1.1g/ml of lambdacarrageenan, 14.1±0.7g/ml (23.5± of remdesivir). 1.2M), lambdacarrageenan showed more than 15 times excellent activity.
In addition, in an influenza A and B virus test conducted on MDCK cells (cells derived from dog kidney epithelium), lambdacarrageenan showed similar or superior antiviral activity to previously known chemicals.
Lambdacarrageenan also showed excellent results in SI indicating safety versus efficacy. SI is an index showing the ratio of antiviral activity to cytotoxicity, and the higher the value, the more effective and safe ingredients are evaluated.
An official from Hanmi Pharm, who participated in the study, said, “In the pandemic situation where Corona 19 is spreading, personal quarantine is emphasized above all.” “Hanmi cold mask nasal spray can effectively block virus penetration through the nose, so it is combined with KF94 mask. If used, it will be an effective personal defense tool.”