[헬스코리아뉴스 / 박원진] Patients on hemodialysis appear to be particularly careful in the occurrence of fractures. This is because the risk of myocardial infarction increases when a fracture occurs. Myocardial infarction also poses a risk of death.
The Korean Society of Nephrology (Chairman Chul-Woo Yang, Catholic University of Medicine Seoul St. Mary’s Hospital) analyzed the data from the Health Insurance Review and Assessment Service, out of a total of 38,935 (1379 hemodialysis patients, 27,556 chronic kidney disease patients before dialysis). Fractures occurred in 5057 (13%), and 1431 (3.7%) of them reported acute myocardial infarction.
In particular, hemodialysis patients with vertebral fractures were found to have twice the risk of developing myocardial infarction compared to non-fractured groups.
The reason why fracture and acute myocardial infarction are correlated in hemodialysis patients is that various factors affecting vascular calcification and bone strength (hyperphosphatemia, elevated FGF-23, decreased vitamin D, hyperparathyroidism, etc.) in hemodialysis patients. This is because it acts as a cause of increasing myocardial infarction as well as fractures. For example, hypotension and ischemic injury during dialysis may additionally increase myocardial infarction.
Professor Kwon Young-ju, a professor at Korea University Guro Hospital, who led the study, said, “In chronic kidney disease patients, more attention is required for bone health, including bone density.” “It is necessary to monitor the occurrence of acute myocardial infarction in hemodialysis patients with fractures. “I said.
Prof. Kwon added the meaning as “an important research result suggesting the association with cardiovascular disease and establishing basic data on fracture management in dialysis patients.”
The Korean Society of Nephrology’s Chronic Kidney Disease Mineral-Bone Disease Research Group (Chairman: Jeong-Woo Noh, Department of Renal Internal Medicine, Hallym University of Medicine) has ▲confirmed the significance of bone density testing in domestic dialysis patients, and guidelines for strengthening bone density ▲Managing guidelines for vascular calcification through improvement of mineral indicators ▲ Active research is underway such as identifying the role of trace elements in buffering the progress of vascular calcification and management guidelines. This research was conducted as a collaborative research project supported by the Korean Nephrology Association, and was published online in OSTEOPOROSIS INTERNATIONAL.
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