[천지일보=이수정 기자] Research results that the main component of Hanmi’s’Hanmi Cold Mask Nasal Spray’, a respiratory virus blocker applied to the nose, effectively blocks the COVID19 virus, have been listed in international journals.
Scientific Reports, an SCI-level international academic journal published by Nature, was conducted by the Korea Research Institute of Chemical Technology with the support of the Ministry of Science, Technology, and Communication.’In vitro cell experiment evaluating the antiviral activity of lambdacarrageenan ingredients’ The result paper was published on the 12th.
Lambdacarrageenan, a naturally derived ingredient extracted from seaweed, is the main ingredient in the recently launched Hanmi Cold Mask Nasal Spray by Hanmi Pharmaceutical.
According to the paper, the researchers used’EC50′ (50% effective concentration) as an index for evaluating the antiviral activity of lambdacarrageenan against the virus that causes COVID19 (SARS-CoV-2) and influenza viruses A and B, which are the main causes of pandemic flu. ) And’SI’ (Selectivity Index) were used.
First, in the SARS-CoV-2 virus test conducted in Vero cells, the EC50 values indicating antiviral activity were 0.9±1.1 μg/ml of lambdacarrageenan, and 14.1±0.7 μg/ml of remdesivir, showing that lambdacarrageenan showed more than 15 times superior activity. Confirmed to be visible.
In addition, in influenza A and B virus tests conducted on MDCK cells, lambdacarrageenan showed similar or superior antiviral activity to previously known chemicals.
In addition, it was confirmed that lambdacarrageenan showed excellent results in SI, which shows safety versus efficacy, as well as its efficacy and safety. SI is an index showing the ratio of antiviral activity to cytotoxicity, and the higher the value, the more effective and safe ingredients are evaluated.
An official from Hanmi Pharm who participated in this study said, “In the pandemic situation where COVID19 is spreading, personal quarantine is emphasized above all.” “Hanmi cold mask nasal spray can effectively block virus penetration through the nose, so it can be used in parallel with KF94 mask. In this case, it will be an effective means of personal quarantine.”
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