Korea University Professor Hyun-Tae Park Team
The first study of polycystic ovary syndrome using domestic big data
Establishing standards for establishing clinical guidelines
In Korea, the number of women of childbearing age who are diagnosed with polycystic ovary syndrome is steadily increasing every year.
Polycystic ovary syndrome is a common endocrine disease that occurs in about 10% of women of childbearing age. Chronic anovulation, menstrual abnormalities, irregular bleeding, etc. appear, and is a major cause of infertility.
In general, polycystic ovary syndrome patients are often obese, and thus various metabolic diseases have been known to increase. However, in a recent study, it was found through big data that Korean women have a high percentage of normal weight even with polycystic ovary syndrome, and that having polycystic ovary syndrome alone increases the risk of developing type 2 diabetes regardless of obesity. .
A recent study by Professor Hyun-Tae Park of the Department of Obstetrics and Gynecology at Anam Hospital, Korea University (Prof. Confirmed that. The research team analyzed data for 10 years from 2003 to 2012 of 6,811 women aged 15 to 44 through the National Health Insurance sample cohort database. As a result of dividing into 1,136 people with polycystic ovary syndrome and 5,675 control groups, women with polycystic ovary syndrome had a 2.6-fold increase in risk of developing type 2 diabetes compared to women without polycystic ovary syndrome. On the other hand, there was no significant relationship between body mass index, family history, and cholesterol levels.
The greatest significance of this study is that it has prepared a basis for presenting guidelines suitable for Koreans using domestic big data. A Finnish birth cohort study found that type 2 diabetes increased only in obese cases of polycystic ovary syndrome, whereas in Australia, type 2 diabetes was also increased regardless of BMI. This may appear differently depending on the characteristics of the country, race, etc., suggesting the need for guidelines tailored to Koreans.
Professor Ryu Ki-jin said, “Existing studies were mainly conducted on Western women with a high proportion of obese polycystic ovary syndrome, and studies using Korean data with relatively low prevalence of obesity were insufficient.” Through the diagnosis of polycystic ovary syndrome, we hope that it will serve as an opportunity to reorganize treatment processes and guidelines for the prevention and management of metabolic diseases.”
Prof. Kijin Ryu also explained, “If you have been diagnosed with polycystic ovary syndrome, you will need consultation and early management about the risk of diabetes.” It is advisable to keep your health through accurate diagnosis and prescription.”
Meanwhile, this study’Risk of type 2 diabetes is increased in nonobese women with polycystic ovary syndrome: the National Health Insurance Service-National Sample Cohort Study’ is published in the latest issue of the American Society of Reproductive Medicine, Fertility and Sterility, and is attracting international attention.