Daewoong Pharmaceutical’s Hoy Star tablet showed a corona treatment effect. Why?

According to Daewoong Pharmaceutical, this clinical trial was conducted in a placebo-controlled, randomized, and double-blind method for a total of 89 mild or asymptomatic confirmed patients hospitalized with Corona 19, with the participation of professor Myung-don Oh, Seoul National University, and researchers from 13 institutions. . A total of 81 patients (41 patients in the Hoystar group, average age 55 years old / 40 patients in the placebo group, average age 43 years old), excluding dropouts, were compared to analyze clinical efficacy and safety.

Daewoong Pharmaceutical said, “The time taken until the virus negative prevalence, the main evaluation variable, was not statistically significant, but the rate at which the virus was removed tended to be faster in the Hoystar group than in the placebo group.”

It turns out that Hoystar’s mechanism of action is not a drug that directly kills the virus, but a mechanism that blocks the entry of the virus into the cell (TMPRSS2 inhibitor). As a result of the analysis of the ordinal scale and the NEWS score, the time taken to improve the patient’s clinical symptoms showed a tendency to recover faster in the Hoystar group. Therefore, as the result of improvement of the symptom scale has great clinical significance, detailed analysis will be conducted.